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Research articles

Signatures of ambient pressure superconductivity in thin film la 3 ni 2 o 7.

Harold Y. Hwang

A reinforced lunar dynamo recorded by Chang'e-6 farside basalt

Rixiang Zhu

Ancient genomes reveal a deep history of treponemal disease in the Americas

Rodrigo Barquera
T. Lesley Sitter
Kirsten I. Bos

Scalable production of ultraflat and ultraflexible diamond membrane

Edge-exposed exfoliation using sticky tape is shown to be a simple and reliable method for scaling up the production of ultrathin, ultraflat and ultraflexible polycrystalline diamond membranes for diverse electrical, optical, mechanical, thermal, acoustic and quantum applications.

Jixiang Jing
Fuqiang Sun

Nucleosome fibre topology guides transcription factor binding to enhancers

Motif grammar on nucleosome fibres acts as signpost elements, directing TF combinatorial binding to enhancers.

Michael R. O’Dwyer
Meir Azagury
Abdenour Soufi

Lithocholic acid phenocopies anti-ageing effects of calorie restriction

Lithocholic acid is one of the metabolites upregulated during calorie restriction, and treatment of mice, worms and flies with this bile acid alone can reproduce the health benefits of calorie restriction.

Sheng-Cai Lin

Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing

The molecular mechanism underlying how lithocholic acid recapitulates the lifespan and healthspan benefits of calorie restriction is revealed to involve TULP3, sirtuins, v-ATPase and AMPK.

The conformational space of RNase P RNA in solution

Using a deep neural network and statistical analyses of atomic force microscopy images of individual RNA molecules enables the mapping of RNA conformational space in solution.

Yun-Tzai Lee
Maximilia F. S. Degenhardt
Yun-Xing Wang

229 ThF 4 thin films for solid-state nuclear clocks

Laser excitation of the 229 Th isomer, potentially relevant for nuclear clocks, is reported in thorium fluoride thin films, which are less radioactive and amenable to integration compared with existing thorium-doped crystals.

Chuankun Zhang
Lars von der Wense
Eric R. Hudson

Trimodal thermal energy storage material for renewable energy applications

A eutectic phase change material composed of boric and succinic acids demonstrates a transition at around 150 °C, with a record high reversible thermal energy uptake and thermal stability over 1,000 heating–cooling cycles.

Saliha Saher
Sam Johnston
Karolina Matuszek

Diatom phytochromes integrate the underwater light spectrum to sense depth

This study demonstrates that diatoms with phytochrome photoreceptors can detect and functionally respond to the entire visible light spectrum through these sensors, enabling them to sense depth and regulate photosynthesis accordingly in marine environments.

Carole Duchêne
Jean-Pierre Bouly
Marianne Jaubert

Spatial transcriptomic clocks reveal cell proximity effects in brain ageing

A spatially resolved single-cell transcriptomics map of the mouse brain at different ages reveals signatures of ageing, rejuvenation and disease, including ageing effects associated with T cells and rejuvenation associated with neural stem cells.

Eric D. Sun
Olivia Y. Zhou
Anne Brunet

Terahertz field-induced metastable magnetization near criticality in FePS 3

Intense terahertz pulses are used to induce metastable magnetization with a remarkably long lifetime of more than 2.5 milliseconds in a van der Waals antiferromagnet, FePS 3 .

Batyr Ilyas
Tianchuang Luo

Hierarchical design of pseudosymmetric protein nanocages

A new computational method for design of pseudosymmetric self-assembling protein nanomaterials has resulted in purification of cage-like protein assemblies containing 960 subunits with a diameter of 96 nm.

Quinton M. Dowling
Young-Jun Park
Neil P. King

Timely TGFβ signalling inhibition induces notochord

Through analysis of developing chick embryos and in vitro differentiation of embryonic stem cells, a study develops a method to generate a model of the human trunk with a notochord.

Ashley R. G. Libby
James Briscoe

Engineered extrachromosomal oncogene amplifications promote tumorigenesis

Large extrachromosomal DNAs are engineered using a CRISPR- and Cre– loxP -based approach and shown to drive cancer in mouse models, with potential applications in determining the role of oncogene amplifications in human cancers.

Davide Pradella
Minsi Zhang
Andrea Ventura

Atmospheric rivers cause warm winters and extreme heat events

Seasons with more frequent atmospheric rivers (ARs) also have warmer than average temperatures in many mid-latitude regions, and AR events are associated with temperature anomalies of 5–10 °C above the climatological mean.

Serena R. Scholz
Juan M. Lora

Determining structures of RNA conformers using AFM and deep neural networks

HORNET, a method that uses unsupervised machine learning and deep neural networks to analyse atomic force microscopy data enables structural determination of RNA molecules in multiple conformations.

Hermann F. Degenhardt

Synaptic basis of feature selectivity in hippocampal neurons

A temporally asymmetric synaptic plasticity kernel results from bidirectional modifications of synaptic weights around the induction of a place field.

Kevin C. Gonzalez
Adrian Negrean
Attila Losonczy

Tidally driven remelting around 4.35 billion years ago indicates the Moon is old

Lunar rock and zircon ages were reset by a remelting event driven by the Moon’s orbital evolution, reconciling existing discrepancies in estimates for the formation time of the Moon and the crystallization time of its magma ocean.

Francis Nimmo
Thorsten Kleine
Alessandro Morbidelli

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Browse Articles

Publisher correction: thioflavin-t: application as a neuronal body and nucleolar stain and the blue light photo enhancement effect.

Jin-Hong Min
Heela Sarlus
Robert A. Harris

Author Correction: Performance prediction of sintered NdFeB magnet using multi-head attention regression models

Qichao Liang

Author Correction: A qualitative study exploring the clinical phenomenology and impact of hypersexuality in patients with Parkinson’s Disease

Natalie Tayim
Jalesh N. Panicker
Walaa G. El Sheikh

Author Correction: Epitaxial growth of high-quality GaN with a high growth rate at low temperatures by radical-enhanced metalorganic chemical vapor deposition

Arun Kumar Dhasiyan
Frank Wilson Amalraj
Masaru Hori

Noise pollution mitigation and control in urban areas near international borders through 2D noise mapping

Pervez Alam
Tarique Ahmad
Mufeed Sharholy

Alleviation of drought stress in tomato by foliar application of seafood waste extract

Imen Ben Sedrine
Sirine Werghi
Faten Gorsane

Genetic correlation and mendelian randomization reveal the impact of sleep traits on urolithiasis risk

Zhe-xin Zhang
Cheng-yi Liu

Potential therapeutic effects of IL28RA inhibition on acute myocardial infarction through phosphorylated JAK1/STAT1 signaling pathways

Xiangxuan Chen

Research on the low-temperature performance of basalt fiber- rubber powder modified asphalt mixtures under freeze-thaw in large temperature differences region

Yuefeng Zhu

Estimating global geographical distribution and ecological niche dynamics of Ammannia coccinea under climate change based on Biomod2

YanJing Zhang

Epidemiological landscape of tongue cancer in younger patients in a National Cancer Center in Brazil

Ana Carolina da Silva Souto
Beatriz Nascimento Monteiro da Silva
Daniel Cohen Goldemberg

Interval variational approach for production control and waste reduction using artificial hummingbird algorithm

Subhajit Das
Adel Fahad Alrasheedi
Seyedali Mirjalili

Author Correction: Spatiotemporal dynamic assessment and obstacle analysis of economic resilience in China’s marine fisheries

Shou-Yi Qiao

Publisher Correction: Web log mining techniques to optimize Apriori association rule algorithm in sports data information management

Tiantian Li

Author Correction: Frequency and spectrum of mutations in human sperm measured using duplex sequencing correlate with trio-based de novo mutation analyses

Jonatan Axelsson
Danielle LeBlanc
Carole Yauk

Retraction Note: Detection of hate: speech tweets based convolutional neural network and machine learning algorithms

Hameda A. Sennary
Ghada Abozaid
Alexey Mikhaylov

Publisher Correction: Genetically predicted gut bacteria, circulating bacteria-associated metabolites and pancreatic ductal adenocarcinoma: a Mendelian randomisation study

Neil Daniel
Riccardo Farinella
Daniele Campa

Publisher Correction: Development and characterization of a self-nano emulsifying drug delivery system (SNEDDS) for Ornidazole to improve solubility and oral bioavailability of BCS class II drugs

Popat Mohite
Shruti Sule
Okechukwu N. N. Okoye

Deceleration capacity derived from a five-minute electrocardiogram predicts mortality in the general population

Alexander Steger
Petra Barthel
Georg Schmidt

Long-term effects of adding biochar to soils on organic matter content, persistent carbon storage, and moisture content in Karagwe, Tanzania

Baraka Ernest
Pius Z. Yanda
Mathias Fridahl

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